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SEIZURES The FDAapproved CBD as a treatment for seizures as its action on sodium channels inthe brain reduce symptoms for people with epilepsy.*14,15

ANXIETY Brainimaging studies show that CBD creates brain activity patterns that loweranxiety and help with a variety of anxiety disorders.*5-9

DIABETES CBD hasbeen shown to help protect diabetics by reducing brain and pancreasinflammation, thus reducing the incidence of diabetes.*16-18

DEPRESSION Researchhas shown that CBD may provide quick antidepressant effects through its actionson neurotransmitters in the brain such as serotonin and glutamate.*10,11

CARDIOVASCULARDISEASE CBD may improve heart health by protecting against vascular damagethanks to its impact on the immune system and the ability to reduceinflammation.*19,20

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1. The non-psychoactive cannabis componentcannabidiol is an oral anti-arthritic treatment for collagen-induced arthritisin mice. PNAS

2. Boundaries | Cannabidiol alleviates anexperimental autoimmune encephalomyelitis model of multiple sclerosis byinducing myelosuppressive cells. Immunology (frontiersin.org)

3. Reducing Pain and Nerve Injury in RatOsteoarthritis by Cannabidiol During the Early Inflammatory Phase (nih.gov)

4.Cannabidiol (CBD) for the Treatment of Acute and Chronic Low Back Pain: A CaseSeries and Literature Review – PubMed (nih.gov.)

5. Effects of ipsapiron and cannabidiolon experimental anxiety in humans – PubMed (nih.gov)

6. Cannabidiol as a Potential Treatmentfor Anxiety Disorders (nih.gov)

7. On Anxiety Memory Impairment Due toReconsolidation Inhibition: Insights from Cannabidiol Treatment. - ExecutiveSummary - European PMC

8. Anxiolytic Effects of Cannabidiol inthe Elevated Plus Maze - PubMed (nih.gov)

9. Translational Research on theTherapeutic Potential of Cannabidiol (CBD):

10. Towards a New Era - PubMed ( nih.gov)Ten Prohedonic Effects of Cannabidiol in a Rat Model of Depression - PubMed(nih.gov)

11. Cannabidiol Induces Rapid-ActingAntidepressant-Like Effects and Enhances Cortical 5-HT/GlutamateNeurotransmission: 5- Role of HT1A Receptors - PubMed (nih.gov) )

12. A Systematic Review of the Effects ofCannabidiol on Cognitive Function: Relevance to Schizophrenia - PubMed(nih.gov)

13. Cannabidiol (CBD) as AdjunctiveTherapy in Schizophrenia: A Multicenter Randomized Controlled Trial -PubMed(nih.gov)

14. FDA approves first drug containingmarijuana-derived active substance for treatment of rare, severe epilepsy | FDA15

Abnormal Mutant Nav1.6 Sodium ChannelActivity Associated with Epilepsy Can Be Suppressed by Cannabidiol | Brain |Oxford Academic (oup.com)

16. Effects of cannabidiol on diabeticoutcomes and chronic cerebral hypoperfusion comorbidities in middle-aged rats -PubMed (nih.gov)

17. Experimental cannabidiol treatmentattenuates early pancreatitis in type 1 diabetes - PubMed (nih.gov) gov)

18. Cannabidiol Reduces PancreaticInflammation Diabetes Incidence in Nonobese Diabetic Mice – PubMed (nih.gov)

19. Is the cardiovascular system atherapeutic target for cannabidiol?

20. Therapeutic Use of Cannabinoids inCardiomyopathy and Heart Failure – PubMed (nih.gov)

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